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Every individual has suffered from some kind of a pains in their lifetime and might have taken one of the most popular combination aceclofenac paracetamol serratiopeptidase. But before taking them, have you ever given a thought that how this amazing combination works? Here we’ll educate you all about aceclofenac paracetamol serratiopeptidase uses, mechanism of action, side effects and other information.

Different combination of NSAIDs is available in the market, one of the potent combinations is Aceclofenac, Paracetamol and Serratiopeptidase. One of the most preferred combination for the management of conditions like headache, mild migraine, menstrual pain and musculoskeletal pain.

So let us apprise you, in detail about Aceclofenac, Paracetamol and Serratiopeptidase combination.

Aceclofenac Paracetamol and Serratiopeptidase

Aceclofenac + Paracetamol + Serratioptidase is a combination of drug therapy and is available in the market in the form of a tablet. This combination has Aceclofenac a potent NSAID, Paracetamol a potent pain killer (analgesic), fever-reducing (antipyretic) drug and Serratiopeptidase a proteolytic enzyme having anti-inflammatory and antipyretic properties. It is a Schedule H (prescription) drug and useful for the management of mild to moderate pain and inflammation like body pain, menstrual pain, headache and mild migraine pain.

How does it work?

Aceclofenac Paracetamol Serratiopeptidase have a different mechanism of action.

1. Effects of aceclofenac include reduction of pain and inflammation by inhibiting cyclooxygenase enzyme (COX-1 and COX-2) that promotes the synthesis of prostaglandins which are the chemical messengers that promotes inflammation essential for wound healing, supports blood clotting functions of platelets.

2. Paracetamol possesses analgesic and antipyretic properties. It produces analgesia by blocking chemical messengers in the brain that causes pain and show antipyretic activity by acting on temperature regulating system of the brain.

3. Serratiopeptidase decreases pain, but by a different mechanism, it mainly prevents the release of pain-producing compound, bradykinin from inflamed tissues. It reduces swelling of infected tissue by draining the fluid from tissue and promote healing of wounds by breaking abnormal proteins present at the site of inflammation.

Aceclofenac Paracetamol Serratiopeptidase Uses
The combination of Aceclofenac, Paracetamol and Serratiopeptidase are mainly used for the treatment and management of a vast number of conditions, mainly for;

  • Fever and flu
  • Bone and joint pain
  • Rheumatoid Arthritis
  • Osteoarthritis
  • Headache
  • Mild migraine pain
  • Toothache
  • Ankylosing spondylitis
  • Menstrual pain
  • Cold and sore throat
  • Inflammation (swelling)


These are some side-effects that may be associated with Aceclofenac Paracetamol Serratiopeptidase Uses

  • Abdominal pain
  • Dizziness
  • Emesis (vomiting)
  • Dyspepsia (indigestion)
  • Allergic reaction (skin redness and rashes)
  • Loss of appetite
  • Hepatic (liver) damage

Discontinue the medication if any of the above shown or any other unusual effects are experienced.


As this is Schedule H medication so always consult your physician before taking Aceclofenac, Paracetamol and Serratiopeptidase tablets. Moreover, inform your doctor about any pre-existing diseases, current medication, any prior episodes of allergic reaction towards NSAIDs, breastfeeding or surgery.